Research Applications of Species Specific CRP ELISA Kits

&The value of C-reactive protein in pre-clinical and clinical research is well established, and our species-specific CRP kits have a proven track record in important areas such as autoimmune and cardiovascular diseases, nutrition and toxicology research and a growing field of new applications. These specialized kits are also adapted for investigational work involving urine and other body fluids and tissues as well as culture supernatants. Please ask for our assistance in developing special protocols (modification of existing kits or novel assays) that can expand your research goals and enable you to discover additional dimensions to your findings. Package inserts, product brochure, and published literature are always available by request: info@helica.com.

DETECTION RANGE

C-Reactive Protein, Canine.................3.6 - 40 ng/mL
C-Reactive Protein, Rat.....................2.5 - 133 ng/mL
C-Reactive Protein, Human.................0.12 - 10 ng/mL
C-Reactive Protein, Mouse..................1.56 - 25 ng/mL
C-Reactive Protein, Primate................0.12 - 10 ng/mL
C-Reactive Protein, Rabbit..................1.56 - 25 ng/mL

View our C-Reactive Protein Kits product page

View our product reviews on Rat CRP ELISA

View our product reviews on Dog CRP ELISA

RECENT CITATIONS WITH HELICA BIOSYSTEMS CRP KITS

Dumas, J-F. N-3 PUFA-Enriched Diet Delays the Occurrence of Cancer Cachexia in Rat With Peritoneal Carcinosis. Nutrition and Cancer. 2010; 62:343-350.

Lin, K.C. Biogenic Nanoporous Silica-based Sensor For Enhanced Electrochemical Detection Of Cardiovascular Biomarkers Proteins. Biosensors And Bioelectronics. 2010; 25:2336-2342

Ferreira , L. Effects Of Sitagliptin Treatment On Dysmetabolism, Inflammation And Oxidative Stress In An Animal Model Of Type 2 Diabetes (ZDF Rat). Hindawi Publications. 2010

Nagatomo, F. et.al., Effects Of Exposure To Hyperbaric Oxygen On Oxidative Stress in Rats With Type II Collagen-Induced Arthritis. Clinical And Experimental Medicine. 2009; 10:7-13

Piloto, N. Erythropoietin Promotes Deleterious Cardiovascular Effects And Mortality Risk In A Rat Model Of Chronic Sports Doping. U.S. National Library of Medicine. 2010

Linz Wolfgang, Wohlfart Paulus, Baader Manuel, et.al. The Peroxisome Proliferator-activated Receptor- (PPAR- ) Agonist, AVE8134, Attenuates the Progression of Heart Failure and Increases Survival in Rats. Acta Pharmacologica Sinica. 2009; 30: 935-946

Stokes Karen Y., Dugas Tammy R., Tang Yaoping, et.al. Dietary Nitrite Prevents Hypercholesterolemic Microvascular Inflammation and Reverses Endothelial Dysfunction. AJP - Heart And Circulatory Physiology. 2009; 296:H1281-H1288

MagnÈa JoÎlle, Mariottia FranÁois, Fischera Romy, et.al. Early Postprandial Low-grade inflammation After High-fat Meal In Healthy Rats: Possible Involvement of Visceral Adipose Tissue. The Journal of Nutritional Biochemistry. 2009

Desai Mina, Gayle Dave A., Casillas Ederlen, et.al. Early Undernutrition Attenuates the Inflammatory Response In Adult Rat Offspring. Journal of Maternal-Fetal and Neonatal Medicine. 2009; 22(7):571-575

Driscoll DF, Ling PR, Andersson C, Bistrian BR., et.al. Hepatic Indicators of Oxidative Stress and Tissue Damage Accompanied By Systemic Inflammation in Rats Following a 24-hour Infusion of an Unstable Lipid Emulsion Admixture. JPEN J Parenter Enteral Nutr. 2009; 33(3):327-335

Ortiz R., et. al. Aldosterone Receptor Antagonism Reduces Urinary C-Reactive Protein Excretion in Angiotensin II-Infused. Hypertensive Rats. Journal of the American Society of Hypertension. 2009; 3:184-191

Magee, Thomas R., et. al. Down-regulation of Transcription Factor Peroxisome Proliferator-activated Receptor In Programmed Hepatic Lipid Dysregulation and Inflammation In Intrauterine Growth-restricted Offspring. American Journal of Obstetrics and Gynecology. 2008; 271:271e1-271e5

Veiga, A. P. M., et. al. Association of Canine Obesity With Reduced Serum Levels of C-reactive Protein. Journal of Veterinary Diagnostic Investigation. 2008; 20:224-228

Clements John D., Jamali Fakhreddin, Pravastatin Reverses The Down-regulating Effect of Inflammation on β-Adrenergic Receptors: A disease-drug Interaction Between Inflammation, Pravastatin, and Propranolol. Vascular Pharmacology. 2007; 46(1):52-59

Teixiera de Lemos. E. et. al. Exercise Training Is Adiponectin in ZDF (type 2) Diabetic Rats. Med. Sci. Monit. 2007; 13: 168-174

Cai, X. et. al. The Comparative Study of Sprague-Dawley and Lewis Rats In Adjuvant-induced Arthritis. Arch. Pharmacol. 2006; 373:140-147

Chen, K. et. al. Induction of Leptin Resistance Through Direct Interaction of C-reactive Protein with Leptin. Nature Medicine. 2006; 12:425 - 432 (Human CRP)

Cho W. C., et. al. Altered Expression of Serum Protein In Ginsenoside Re-treated Diabetic Rats Detected By SELDI-TOF MS. Journal of Ethnopharmacology. 2006; 108(2):272-279

Cho W. C. et. al. Differential Expression of Proteins in Kidney, Eye, Aorta, and Serum of Diabetic and Non-
diabetic Rats. J. Cell. Biochem. 2006; 99:256-268

Kalani, R., et.al. Effects of Caloric Restriction and Exercise on Age-Related, Chronic Inflammation Assessed
by C-Reactive Protein and Interleukin-6Effects of Caloric Restriction and Exercise on Age-Related, Chronic
Inflammation Assessed by C-Reactive Protein and Interleukin-6. Journal of Gerontology. 2006; 61A:3:211-217

Lei Yu-Chen, Hwang Jing-Shiang, Chana Chang-Chuan, et.al.
Enhanced Oxidative Stress and Endothelial Dysfunction In Streptozotocin-diabetic Rats Exposed To Fine Particles. Environmental Research. 2005; 99(3):335-343

Buduneli, E. et. al. Systemic Low-Dose Doxycycline and Alendronate Administration and Serum Interleukin-
1Beta, Osteocalcin, and C-Reactive Protein Levels in Rats. Journal of Periodontology. 2005;76:1927-1933

Ling, S. and F. Jamali. Effect of Early Phase Adjuvant Arthritis on Hepatic P450 Enzymes and Pharmacokinetics of Verapamil: An Alternative Approach to the Use of An Animal Model for Inflammation for Pharmacokinetic Studies. Drug Metabolism and Disposition. 2005; 33:579-586

Shagdarsuren, E. et al. Complement Activation in Angiotensin II-Induced Organ Damage. Circ Res. 2005; 97:716-724

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